Pathophysiology and management of bisphosphonate-related osteonecrosis of the jaw
نویسندگان
چکیده
منابع مشابه
Bisphosphonate-related osteonecrosis of the jaw
Bisphosphonates (BPs) have been used for the management of bone metabolic diseases. Currently their therapeutic use has increased, as also have their adverse effects, one of the most important being the bisphosphonate-related osteonecrosis of the jaw (BRONJ), a complication of diffi cult treatment and solution. Until now, the physiopathology of BRONJ remains unclear, and its treatment is uncert...
متن کاملBisphosphonate-Related Osteonecrosis of the Jaw: Specificities
Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a severe complication that has recently emerged in patients treated with intravenous bisphosphonates for malignant diseases. This complication usually presents after a minor local trauma during a dental treatment. Several etiopathogenic mechanisms of this pathological condition have been proposed, but no model can explain all morpholog...
متن کاملBisphosphonate-Related Osteonecrosis of the Jaw.
Bisphosphonates are agents commonly used in the treatment of osteoporosis, and in the management of metastatic bone disease, and of hypercalcaemia of malignancy. Any oral surgical procedure or traumatic event exposing bone to bacterial infection may precipitate osteonecrosis of the jaw in subjects who have been treated with bisphosphonates which suppress bone turnover and inhibit the angiogenes...
متن کاملOsteoporosis and Bisphosphonate-Related Osteonecrosis of the Jaw Bone
The aim of this longitudinal study is to present data from 76 female patients treated with bisphosphonates (BPs) for postmenopausal osteoporosis and referred to the Unit of Oral Diagnosis and Day Surgery of the University of Milano for diagnosis and treatment. All patients received a thorough oral examination. The diagnosis of osteonecrosis of the jaw bone (ONJ) was made from radiographic and c...
متن کاملBisphosphonate-related osteonecrosis of the jaw and dental implants
Bisphosphonate (BP) is one of the possible riskfactors in the osteonecrosis of the jaw (ON J). Surgical interventions during or after the course of treatment by using BPs may expose the patient under this risk. Animal studies, human studies, case reports, and systematic reviews are used to show the relationship between the use of bisphosphonates and dental implants. In this review data about bi...
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ژورنال
عنوان ژورنال: Japanese Journal of Oral and Maxillofacial Surgery
سال: 2010
ISSN: 0021-5163,2186-1579
DOI: 10.5794/jjoms.56.286